ProZinc U40, 10 ml, Rx

Recommended dosages only. Always follow the directions for dosing and administration from your veterinarian.

Use of a syringe other than a U-40 syringe will result in incorrect dosing.
For subcutaneous injection in cats only.

ProZinc insulin should be mixed by gently rolling the vial prior to withdrawing each dose from the vial. Using a U-40 insulin syringe, the injection should be administered subcutaneously on the back of the neck or on the side of the cat.

The initial recommended ProZinc dose is 0.1 - 0.3 IU insulin/pound of body weight (0.2 - 0.7 IU/kg) every 12 hours. The dose should be given concurrently with or right after a meal. The veterinarian should re-evaluate the cat at appropriate intervals and adjust the dose based on both clinical signs and glucose nadirs until adequate glycemic control has been attained. In the effectiveness field study, glycemic control was considered adequate if the glucose nadir from a 9-hour blood glucose curve was between 80 and 150 mg/dL and clinical signs of hyperglycemia such as polyuria, polydipsia, and weight loss were improved.

Further adjustments in the dosage may be necessary with changes in the cat's diet, body weight, or concomitant medication, or if the cat develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.

Storage Conditions: Store in an upright position under refrigeration at 36-46°F (2-8°C). Do not freeze. Protect from light.

Each mL contains: -recombinant human insulin 40 International Units (IU)
-protamine sulfate 0.466 mg
-zinc oxide 0.088 mg
-glycerin 16.00 mg
-dibasic sodium phosphate, heptahydrate 3.78 mg
-phenol (added as preservative) 2.50 mg
-hydrochloric acid 1.63 mg
-water for injection (maximum) 1005 mg
pH is adjusted with hydrochloric acid and/or sodium hydroxide.

Caution:
Federal law restricts this drug to use by or on the order of a licensed veterinarian.

The safety and effectiveness of ProZinc insulin in breeding, pregnant, and lactating cats has not been evaluated.

Warning:
User Safety: For use in cats only. Keep out of the reach of children. Avoid contact with eyes. In case of contact, immediately flush eyes with running water for at least 15 minutes. Accidental injection may cause hypoglycemia. In case of accidental injection, seek medical attention immediately. Exposure to product may induce a local or systemic allergic reaction in sensitized individuals.

Animal Safety: Owners should be advised to observe for signs of hypoglycemia (see Cat Owner Information Sheet). Use of this product, even at established doses, has been associated with hypoglycemia. An animal with signs of hypoglycemia should be treated immediately. Glucose should be given orally or intravenously as dictated by clinical signs. Insulin should be temporarily withheld and, if indicated, the dosage adjusted.

Any change in insulin should be made cautiously and only under a veterinarian's supervision. Changes in insulin strength, manufacturer, type, species (human, animal) or method of manufacture (rDNA versus animal-source insulin) may result in the need for a change in dosage.

Appropriate diagnostic tests should be performed to rule out other endocrinopathies in diabetic cats that are difficult to regulate.

Keep out of reach of children and animals.

All prescription items are Non-Refundable and Non-Returnable.

Prescription

This item requires a valid prescription from a licensed veterinarian