Vanguard® Plus 5 L4 Cv
Manufacturer: Zoetis, Inc.
This treatment applies to Dogs.
Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine
Modified Live and Killed Virus
Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin
For use in dogs only
Thimerosal free
For vaccination of healthy dogs 6 weeks of age or older as an aid in preventing disease caused by CD virus, CAV-1, CAV-2, CPI virus, CCV, CPV and CPV-2c, Leptospira canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona. Vanguard Plus 5 L4 CV contains attenuated strains of CD virus, CAV-2, CPI virus, CPV, inactivated CCV, and inactivated whole cultures of the four Leptospira serovars mentioned above. The high-titer, low-passage CPV virus in Vanguard Plus 5 L4 CV is highly immunogenic and capable of stimulating active immunity in the presence of maternal antibodies. This product does not contain CPV type 2c. Cross protection against CPV type 2c was demonstrated in vaccinated puppies challenged 5 weeks following second vaccination.
Vaccination and revaccination according to label directions have been demonstrated (under field conditions) to result in serum antibody titers that persist for 12-48 months against CV virus (serum neutralization [SN] titer = 1:32), CAV- 1 (SN = 1:16), CAV-2 (SN = 1:16), CPI virus (SN = 1:16), and CPV (hemagglutination inhibition [HAI] titer = 1:80).
VANGUARD PLUS 5 L4 CV is a freeze-dried preparation of attenuated strains of CD virus, CAV-2, CPI virus, CPV and inactivated whole cell cultures of L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, and L. pomona.
The Leptospirosis fraction is microfiltered 5 times to remove extraneous protein, providing excellent antigen purity and smoothness.
Efficacy confirmed against the most common canine Leptospira serovars.
This item is NON-RETURNABLE and NON-REFUNDABLE.
CALIFORNIA PROPOSITION 65 WARNING 
This product contains chemicals including, Aminoglycosides, which is known to the State of California to cause cancer, birth defects or other reproductive harm. (California law requires this warning to be given to customers in the state of California) For more information go to www.P65Warnings.ca.gov. 
