ToxiBan, Special Order

Dosage:
Suspension and Suspension w/Sorbitol
For small animals, use 10 to 20 mL per kg (5 to 10 mL per pound) body weight. For large animals, use 4 to 12 mL per kg (2 to 6 mL per pound) body weight.

Granules
To make a thin suspension, mix 1 volume measure with 5 to 7 parts cold water (Example: 1 level cup ToxiBan to 6 cups water). Agitate vigorously for 10 to 30 seconds. For small animals, use 2 to 4 grams per kg (1 to 2 grams per pound) body weight. For large animals, use 0.75 to 2.0 grams per kilogram (0.35 to 0.9 grams per pound). One pound (453.6 grams) normally treats an animal weighing 225 to 600 kilograms (500 to 1300 pounds).

Administration:
ToxiBan Suspension and Suspension with Sorbitol may be given directly or mixed with a small amount of cold water to reduce viscosity. For Granule administration, use as a powder in food or dilute to create a suspension. When a suspension is created, agitate frequently to keep liquid uniform. A stomach tube is preferred, but an oral drench may be used in emergency.

Ingredients:
MedChar (activated charcoal, USP), Kaolin, and Sorbitol (in granules and suspension with sorbitol). Suspensions also contain suspending agents and preservatives. Granules contain wetting and dispersing agents.

Precautions:
ToxiBan is an adjunct in the management of poisoning emergencies. Prior to use, proper life support and gastric emptying must be implemented, if indicated. Because more than an hour may pass before ToxiBan can be administered without regurgitation after an emetic has been given, it may be more effective to give ToxiBan immediately because adsorption of a toxicant may be a more effective removal than vomiting. ToxiBan produces black stools. These stools may have a diarrhea consistency and may persist for several hours. Sorbitol can create a profound cathartic effect. Proper attention should be provided to fluid and electrolyte needs to prevent dehydration, possible hypernatremia and even hypotension. ToxiBan Suspension should be used for multiple use, and cathartics should only be used intermittently during multiple dose activated charcoal use.

Contraindications:
There are no known absolute contraindications to the use of activated charcoal. It should not be given simultaneously or shortly before the oral administration of other therapeutic agents such as antibiotics, vitamins or amino acids. Antibiotic therapy should be administered parenterally when ToxiBan is used.