Oxytocin Rx

Dosage:

Obstetrical Use: Inject aseptically by the intravenous, intramuscular or subcutaneous route as follows:

EWES, SOWS:
1.5 to 2.5 mL
30 to 50 USP Units

COWS, HORSES:
5.0 mL
100 USP Units

These dosages are recommended, and may be repeated as indicated.

Milk Let-down:Inject aseptically by the intravenous, intramuscular or subcutaneous route.

COWS:
0.5 to 1.0 mL
10 to 20 USP Units

SOWS:
0.25 to 1.0 mL
5 to 20 USP Units

These dosages are recommended and may be repeated as necessary.

Note: Oxytocin will not induce milk let-down unless the udder is in the proper physiological state.

Ingredients:

Oxytocin injection contains 20 USP Units of oxytocin and less than 0.4 units of presser activity per mL. Each mL of sterile solution also contains 0.9% w/v sodium chloride, 0.5% w/v chlorobutanol (as a preservative), with water for injection q.s. and pH adjusted to 3.0 to 5.0 with acetic acid.

Caution:

Do not use in dystocia due to abnormal presentation of the fetus until correction is accomplished.

Oxytocin is a potent preparation, accordingly, it should be administered with due caution. For prepartum usage full dilation of the cervix should be accomplished either naturally or through the administration of estrogen prior to oxytocin therapy.

Oxytocin acts directly on the smooth musculature of the uterus in all species to induce rhythmic contractions, although in some species the uterine cervix does not respond to oxytocin. The responsiveness of the uterine musculature to oxytocin varies greatly with the stage of the reproductive cycle. During the early phases of pregnancy the uterus is relatively insensitive to the effects of oxytocin, while in the late phases the sensitivity is markedly increased. Most authorities attribute this varying response to the varying levels of estrogen and progesterone during the course of pregnancy.

Oxytocin also has been shown to exert a milk ejecting effect, occasionally referred to as the galactogogic effect. The actual mechanism by which oxytocin stimulates the release of milk from the mammary glands is not known with certainty, but oxytocin is presumed to act on certain smooth muscle elements in the gland.

Store at controlled room temperature.

Do Not Freeze.

Prescription

This item requires a valid prescription from a licensed veterinarian.