Ivomec 1% Dual Parasiticide for Cattle and Swine, 50 ml Injection

Cattle: IVOMEC Injection should be given only by subcutaneous injection under the loose skin in front of or behind the shoulder at the recommended dose level of 200 mcg of ivermectin per kilogram of body weight. Each mL of IVOMEC contains 10 mg of ivermectin, sufficient to treat 110 lb (50 kg) of body weight (maximum 10 mL per injection site).

Body Weight (lb)/Dose Volume (mL):
220 lbs.....2 mL
330 lbs.....3 mL
440 lbs.....4 mL
550 lbs.....5 mL
660 lbs.....6 mL
770 lbs.....7 mL
880 lbs.....8 mL
990 lbs.....9 mL
1100 lbs.....10 mL

Swine: IVOMEC Injection should be given only by subcutaneous injection in the neck of swine at the recommended dose level of 300 mcg of ivermectin per kilogram (2.2 lb) of body weight. Each mL of IVOMEC contains 10 mg of ivermectin, sufficient to treat 75 lb of body weight.

Body Weight (lb)/Dose Volume (mL):
19 lbs.....1/4 mL
38 lbs.....1/2 mL
75 lbs.....1 mL
150 lbs.....2 mL
225 lbs.....3 mL
300 lbs.....4 mL
375 lbs.....5 mL
450 lbs.....6 mL

Administration:

Cattle: IVOMEC Injection is to be given subcutaneously only, to reduce risk of potentially fatal clostridial infection of the injection site. Animals should be appropriately restrained to achieve the proper route of administration. Use of a 16-gauge 1/2 to 3/4” needle is suggested. Inject under the loose skin in front of or behind the shoulder. When using the 200, 500 or 1000 mL pack size, use only automatic syringe equipment.
Use sterile equipment and sanitize the injection site by applying a suitable disinfectant. Clean, properly disinfected needles should be used to reduce the potential for injection site infections.
No special handling or protective clothing is necessary.

Swine: At the time of initiating any parasite control program, it is important to treat all breeding animals in the herd. After the initial treatment, use IVOMEC Injection regularly as follows:
BREEDING ANIMALS
Sows: Treat prior to farrowing, preferably 7-14 days before, to minimize infection of piglets.
Gilts: Treat 7-14 days prior to breeding.
Treat 7-14 days prior to farrowing.
Boars: Frequency and need for treatments are dependent upon exposure. Treat at least two times a year.
FEEDER PIGS
(Weaners/Growers/Finishers)
All weaner/feeder pigs should be treated before placement in clean quarters.
Pigs exposed to contaminated soil or pasture may need retreatment if reinfection occurs.
NOTE:
(1) IVOMEC Injection has a persistent drug level sufficient to control mite infestations throughout the egg to adult life cycle. However, since the ivermectin effect is not immediate, care must be taken to prevent reinfestation from exposure to untreated animals or contaminated facilities. Generally, pigs should not be moved to clean quarters or exposed to uninfested pigs for approximately one week after treatment. Sows should be treated at least one week before farrowing to minimize transfer of mites to newborn baby pigs.
(2) Louse eggs are unaffected by IVOMEC Injection and may require up to three weeks to hatch. Louse infestations developing from hatching eggs may require retreatment.
(3) Consult a veterinarian for aid in the diagnosis and control of internal and external parasites of swine.

WARNING
NOT FOR USE IN HUMANS.
Keep this and all drugs out of the reach of children.

PRECAUTIONS
Transitory discomfort has been observed in some cattle following subcutaneous administration. A low incidence of soft tissue swelling at the injection site has been observed. These reactions have disappeared without treatment. For cattle, divide doses greater than 10 mL between two injection sites to reduce occasional discomfort or site reaction. Use sterile equipment and sanitize the injection site by applying a suitable disinfectant. Clean, properly disinfected needles should be used to reduce the potential for injection site infections.
Observe cattle for injection site reactions. Reactions may be due to clostridial infection and should be aggressively treated with appropriate antibiotics. If injection site infections are suspected, consult your veterinarian.
This product is not for intravenous or intramuscular use.
Protect product from light.
IVOMEC Injection for Cattle and Swine has been developed specifically for use in cattle, swine, reindeer, and American bison only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result. Restricted Drug (California) - use only as directed.
When to Treat Cattle with Grubs
IVOMEC effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. Destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions including the possibility of fatalities. Killing Hypoderma lineatum when it is in the tissue surrounding the esophagus (gullet) may cause salivation and bloat; killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. These reactions are not specific to treatment with IVOMEC, but can occur with any successful treatment of grubs. Cattle should be treated either before or after these stages of grub development. Consult your veterinarian concerning the proper time for treatment. Cattle treated with IVOMEC after the end of the heel fly season may be retreated with IVOMEC during the winter for internal parasites, mange mites, or sucking lice without danger of grub-related reactions. A planned parasite control program is recommended.
Environmental Safety
Studies indicate that when ivermectin comes in contact with soil, it readily and tightly binds to the soil and becomes inactive over time. Free ivermectin may adversely affect fish and certain aquatic organisms. Do not permit water runoff from feed lots to enter lakes, streams or ponds. Do not contaminate water by direct application or by improper disposal of drug containers. Dispose of containers in an approved landfill or by incineration.
As with other avermectins, ivermectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction. The magnitude and duration of such effects are species and life-cycle specific. When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependent insects.