Therapy with Dexamethasone Injectable,2 mg, as with any other potent corticosteroid, should be individualized according to the severity of the condition being treated, anticipated duration of steroid therapy, and the animal's threshold or tolerance for steroid excess.
Treatment may be changed over to Dexamethasone Injectable,2 mg from any other glucocorticoid with proper reduction or adjustment of dosage.
Bovine - Dexamethasone Injectable,2 mg - 5 to 20 mg intravenously or intramuscularly. Dexamethasone Powder may be administered or the parenteral dose repeated as needed.
Equine - Dexamethasone Injectable,2 mg - 2.5 to 5 mg intravenously or intramuscularly. Dexamethasone Powder may be administered or the parenteral dose repeated as needed.
INDICATIONS
Dexamethasone Injectable,2 mg is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in the bovine and equine.
As supportive therapy, Dexamethasone Injectable,2 mg may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. Dexamethasone Injectable,2 mg may be used intravenously as supportive therapy when an immediate hormonal response is required.
Bovine Ketosis
Dexamethasone Injectable,2 mg is offered for the treatment of primary ketosis. The gluconeogenic effects of Dexamethasone Injectable,2 mg, when administered intramuscularly, are generally noted within the first 6 to 12 hours. When Dexamethasone Injectable,2 mg is used intravenously, the effects may be noted sooner. Blood sugar levels rise to normal levels rapidly and generally rise to above normal levels within 12 to 24 hours. Acetone bodies are reduced to normal concentrations usually within 24 hours. The physical attitude of animals treated with Dexamethasone Injectable,2 mg brightens and appetite improves, usually within 12 hours. Milk production, which is suppressed as a compensatory reaction in this condition, begins to increase. In some instances, it may even surpass previous peaks. The recovery process usually takes from 3 to 7 days.
Supportive Therapy
Dexamethasone Injectable,2 mg may be used as supportive therapy in mastitis, metritis, traumatic gastritis, and pyelonephritis, while appropriate primary therapy is administered. In these cases, the corticosteroid combats accompanying stress and enhances the feeling of general well-being.
Dexamethasone Injectable,2 mg may also be used as supportive therapy in inflammatory conditions, such as arthritic conditions, snake bite, acute mastitis, shipping fever, pneumonia, laminitis, and retained placenta.
Equine
Dexamethasone Injectable,2 mg is indicated for the treatment of acute musculoskeletal inflammations such as bursitis, carpitis, osselets, tendonitis, myositis, and sprains. If boney changes exist in any of these conditions, joints, or accessory structures, responses to Dexamethasone Injectable,2 mg cannot be expected. In addition, Dexamethasone Injectable,2 mg may be used as supportive therapy in fatigue, heat exhaustion, influenza, laminitis, and retained placenta provided that the primary cause is determined and corrected.
