Strict hygienic precautions should be taken when handling dogs or feces suspected of harboring E. multilocularis. Infected dogs treated for the first time with Droncit tablets and dogs treated at intervals greater than 28 days may shed eggs in the feces after treatment. The animal should be held in the clinic during this interval and all feces should be incinerated or autoclaved. If these procedures are not possible, the eggs can be destroyed by soaking the feces in a sodium hypochlorite (bleach) solution of 3.75% or greater.6 All areas where the animal was maintained or in contact with should be thoroughly cleaned with sodium hypochlorite and allowed to dry completely before reuse.
The safety index has been derived from controlled safety evaluations, clinical trials and prior approved use in foreign countries. Dosages of 5 times the labeled rate at 14 day intervals to dogs as young as 4 weeks did not produce clinical signs of toxicity. No significant clinical chemistry, hematological, cholinesterase, or histopathological changes occurred. Symptoms of gross overdosage include vomition, salivation, diarrhea and depression.
Praziquantel has been tested in breeding and pregnant dogs. No adverse effects were noted.
Seven instances (3.2%) of either vomiting, anorexia, lethargy or diarrhea were reported during the field trials in which 218 dogs were administered DroncitÂ® Canine Cestocide Tablets. The investigators rated these as non-significant.
For medical emergencies or to report adverse reactions, call 1-800-422-9874.
Keep out of the reach of children. Not for human use. For customer service or to obtain product information, including Material Safety Data Sheet, call 1-800-633-3796.