CattleMaster® GOLD™ FP® 5
Bovine Rhinotracheitis-Viral Diarrhea-Parainfluenza³ -Respiratory Syncytial Virus Vaccine (Modified-Live and Killed Virus)

Advantages

• New with killed BVD Type 2 delivering exceptional respiratory protection even against a lethal challenge.¹
• First and only killed BVD vaccine line with the power to deliver fetal protection from BVD persistent infection and IBR abortion.*
• Temperature-sensitive IBR and PI³ virus strains provide the safety of killed viruses with the protection of modified-live viruses.
• Modified-live BRSV is non-shedding non-immunosuppressive and non-abortigenic.²
• Modified-live strains initiate a balanced immune response providing both a humoral antibody response and a cell-mediated immune (CMI) response.³
• Safe for use in pregnant and open cattle as well as calves of all ages.
• New next-generation adjuvant system PreZent™-A stimulates the immune system to unprecedented protective levels.
• Beef Friendly™ subcutaneous injection.

*Fetal protection when administered prior to breeding. 1-3 Data on file Pfizer Inc

Description
CattleMaster GOLD FP 5 is a freeze-dried preparation of chemically altered strains of IBR and PI³ viruses and modified-live BRSV plus a liquid adjuvanted preparation of inactivated BVD virus strains (Types 1 and 2). The liquid component is used to rehydrate the freeze-dried component. Viral antigens are propagated on an established cell line. This product is adjuvanted with PreZent™-A a proprietary system to ensure consistency of the formulation and enhance the immune response.

Indications
For vaccination of healthy cattle including pregnant cows as an aid in preventing abortion caused by infectious bovine rhinotracheitis (IBR bovine herpesvirus Type 1) persistently infected calves caused by bovine viral diarrhea (BVD) virus Types 1 and 2 and respiratory disease caused by IBR BVD (Types 1 and 2) parainfluenza³ (PI³) and bovine respiratory syncytial virus (BRSV).

Approved Uses
Approved for use in healthy cattle including:

• Pregnant cows and heifers and animals of unknown pregnancy status.
• Calves of any age including calves nursing pregnant cows.

Dosage and Administration

1. General Directions: Vaccination of healthy cattle is recommended. Aseptically rehydrate the freeze-dried vaccine with the liquid component provided shake well and administer 2 mL subcutaneously. In accordance with Beef Quality Assurance guidelines products should be administered in the muscular region of the neck.
2. Primary Vaccination: Administer an initial 2-mL dose followed by a second 2-mL dose 3 weeks later. As an aid in preventing IBR-induced abortion and BVD persistently infected calves administer at approximately 5 and 2 weeks prior to breeding. Calves vaccinated before the age of 6 months should be revaccinated after 6 months of age.
3. Revaccination: Annual revaccination with a single dose is recommended.
4. Good animal husbandry and herd health management practices should be employed.

Precautions

1. Store at 2° - 7° C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.
2. Use entire contents when first opened.
3. Sterilized syringes and needles should be used to administer this vaccine. Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine.
4. Transient local reactions may be observed at the injection site.
5. Burn containers and all unused contents.
6. Do not vaccinate within 21 days before slaughter.
7. Contains gentamicin as preservative.
8. Routine handling of lactating dairy cattle including administration of vaccines such as CattleMaster GOLD FP 5 has been associated with transient reduction in milk production.
9. As with many vaccines anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.
10. This product has been shown to be efficacious in healthy animals. A protective immune response may not be elicited if animals are persistently infected with BVD virus or incubating an infectious disease are malnourished or parasitized are stressed due to shipment or environmental conditions are otherwise immunocompromised or the vaccine is not administered in accordance with label directions.